Which of the following methods is used to taper doses in medically supervised withdrawal?

The correct method for tapering doses in medically supervised withdrawal involves the use of an opioid agonist or an alpha-2 adrenergic agonist. This approach is particularly relevant in the withdrawal management of substances like opioids. Utilizing an opioid agonist can help ease withdrawal symptoms by partially stimulating the same receptors in the brain as the substance being withdrawn from. Alpha-2 adrenergic agonists can assist by providing relief from certain withdrawal symptoms, such as anxiety and agitation, making the process more manageable for the patient. This supervised tapering strategy helps to reduce the intensity of withdrawal, facilitating a safer and more comfortable transition off the medication.

In contrast, the other methods either do not properly address the physiological aspects of withdrawal management or may lead to more severe withdrawal symptoms. Gradual cessation of medication alone may not provide the necessary support to mitigate withdrawal symptoms effectively. Intermittent fasting is unrelated to drug withdrawal and does not serve a purpose in this context. The cold turkey approach is considered unsafe and can lead to significant discomfort and health risks, especially with substances that have a high potential for withdrawal complications. Thus, using agonists or adrenergic agents is the most effective and safe strategy for tapering.